San Francisco 49ers head coach Kyle Shanahan reveals how he's approaching his division rivals without one of the best players ...

This PFF metric shows San Francisco 49ers wide receiver Brandon Aiyuk might be trending in the right direction after a slow ...

Los Angeles Rams coach Sean McVay is "not sad" he doesn't have to game plan for San Francisco 49ers stars Deebo Samuel and ...

Kyle Shanahan isn't always careful with his words. One of these moments happened Wednesday when Shanahan was asked if Brock ...

Now comes the hard part for Kyle Shanahan — devising a game plan without Deebo Samuel and Christian McCaffrey.

SANTA CLARA, Calif. — The San Francisco 49ers have played games without Deebo Samuel Sr. in the last year and a half. And ...

Head coach Kyle Shanahan on Wednesday confirmed in a press conference that Hufanga will get a full practice in to begin the ...

SFGATE columnist Drew Magary still is beaming from the San Francisco 49ers' loss to his favorite team, the Minnesota Vikings.

Given that the calf strain to 49ers running back Christian McCaffrey suddenly and unexpectedly became an Achilles tendon, too ...

The San Francisco 49ers suffered a comprehensive loss against the Minnesota Vikings in Week 2, but Kyle Shanahan isn't ...

Head coach Kyle Shanahan discussed running San Francisco's offense without RB Christian McCaffrey and WR Deebo Samuel Sr., ...

San Francisco 49ers head coach Kyle Shanahan reveals different preparations against the Los Angeles Rams without Aaron Donald ...