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There are 8 to 10 slices in a large Domino's pizza, although that will vary depending on the crust, with the largest going up to 16 slices in the Extra Large New York style.

However, a Domino's pizza slice ranges from 200 calories to 410 calories when it comes to specialty pizzas. Thus, the large MeatZZA is at the higher end while the Cheese pizza is at the lower end.