Inter-organelle communication via the formation of membrane contact sites (MCS) is essential for cell homeostasis. Bacterial pathogens residing in membrane bound vacuoles have exploited this ...

The endoplasmic reticulum (ER)-localized transmembrane proteins IRE1, PERK and ATF6 detect the load of unfolded protein in the lumen of the organelle, serving as stress receptors. They transduce ...

This review explores the role of lysosomal stress in pancreatic diseases, particularly diabetes mellitus. Lysosomes, crucial ...

Technology Networks asked a selection of startups featured in the ELRIG Drug Discovery 2024 Breakthrough Zone how their ...

An international team led by Goethe University Frankfurt has identified an intracellular sensor that monitors the quality of so-called MHC-I molecules, which help the immune system recognize and kill ...

Examples of organelles include the nucleus, the endoplasmic reticulum, the Golgi, mitochondria, vacuoles or lysosomes, and chloroplasts (in plants). After being activated, T lymphocytes must ...

These small organelles generate the energy that fuels nearly every function in the body. According to Dr. Mercola, ensuring your mitochondria are functioning optimally is crucial for sustaining ...

In cells, there is a careful coordination of activity among molecules. Genes have to be expressed in the right cells at the ...