The EMBO Journal2d
Longitudinal autophagy profiling of the mammalian brain reveals sustained mitophagy throughout healthy aging
Aging diminishes autophagy in short-lived model organisms. This study uncouples macroautophagy and mitophagy in the aging ...
University of Manchester24d
Ground-breaking Alzheimer's findings reveal new treatment strategy
‘Astroglia in dementia and Alzheimer’s disease’ in Cell Death and Differentiation. ‘Impaired Adult Neurogenesis in the Dentate Gyrus of a Triple Transgenic Mouse Model of Alzheimer’s’ in PLoS ONE.
eLife12d
Differential growth and transcriptomic profile of stem cell-derived midbrain astrocytes
Dementia Research Institute, School of Medicine, Cardiff University, Hadyn Ellis Building, Maindy Road, Cardiff, CF24 4HQ, UK Neuroscience and Mental Health Innovation Institute, School of Medicine, ...
eLife5d
Sensing the world and its dangers: An evolutionary perspective in neuroimmunology
Detecting danger is key to the survival and success of all species. Animal nervous and immune systems cooperate to optimize danger detection. Preceding studies have highlighted the benefits of ...
Frontiers24d
The leukotriene receptor antagonist montelukast as a potential therapeutic adjuvant in multiple sclerosis – a review
Multiple Sclerosis (MS) is a multifactorial autoimmune disease of the central nervous system (CNS). It is characterized by a heightened activation of the immune system with ensuing inflammation, ...
Frontiers23d
A selective review of inhibitors of protein kinase C gamma: a neuroplasticity-related common pathway for psychiatric illness
Psychotropics are currently developed and marketed with a limited understanding of their mechanism of action. The notion that protein kinase C (PKC) activity is highly relevant to learning and memory ...