Freiburg im Breisgau is the fourth-largest city of the German state of Baden-Württemberg after Stuttgart, Mannheim and Karlsruhe. Its buil…Freiburg im Breisgau is the fourth-largest city of the German state of Baden-Württemberg after Stuttgart, Mannheim and Karlsruhe. Its built-up area has a population of about 355,000, while the greater Freiburg metropolitan area has about 660,000.