Management and investigation of neonatal encephalopathy: 2017 …
WEBThis review discusses an approach to determining the cause of neonatal encephalopathy, as well as current evidence on resuscitation and subsequent management of hypoxic-ischaemic encephalopathy (HIE). Encephalopathy in neonates can be due to varied aetiologies in addition to hypoxic-ischaemia. A combination of careful history, examination and the judicious use of investigations can help ...
Homepage | ADC Fetal & Neonatal Edition
WEB4 days ago · s an edition of ADC from BMJ and RCPCH, publishing perinatal & neonatal medicine research and reviews. Archives of Disease in Childhood: Fetal & Neonatal is a Plan S compliant Transformative Journal. Archives of Disease in Childhood is led by Dr Nick Brown, clinician, epidemiologist and international child health expert.
Neonatal jaundice in infants born at 37 weeks: is NICE treating too ...
WEBNeonatal jaundice affects approximately 60% of term and 80% of preterm infants within the first week of life. Gestation-based treatment threshold graphs by the National Institute of Health and Care Excellence are used to guide jaundice management in the UK.1 NICE treatment thresholds at 37-week gestation are much lower compared with ≥38 weeks and also when compared with the previous and ...
Implementation of an adapted Sepsis Risk Calculator algorithm to …
WEBObjective Assess the impact of introducing a consensus guideline incorporating an adapted Sepsis Risk Calculator (SRC) algorithm, in the management of early onset neonatal sepsis (EONS), on antibiotic usage and patient safety. Design Multicentre prospective study Setting Ten perinatal hospitals in Wales, UK. Patients All live births ≥34 weeks’ gestation over a 12-month period (April 2019 ...
What’s new in the management of neonatal early-onset sepsis?
WEBThe expert guidelines highlighted in this review provide an evidence-based framework for approaching at-risk infants and allow for a more limited and standardised approach to antibiotic use. While these guidelines have significantly reduced antibiotic utilisation worldwide, optimally each unit would individualise their approach to early onset sepsis (EOS) based on the neonatal population they ...
WEBa single CRP value for proven sepsis was 64% (95% CI 53 to. 59) with a positive predictive value of only 14% (95% CI 11 to. 17).45 However, if serial CRP values remain normal, there is a low likelihood of infection with a negative predictive value of nearly 100%46 The 2021 NICE guidelines recommend use of.
Optimising growth in very preterm infants: reviewing the evidence
WEBInfants born before 32 weeks’ postmenstrual age are at a high risk of growth failure. International guidelines have long recommended that they match the growth of an equivalent fetus, despite the challenges posed by ex utero life and comorbidities of prematurity. Several groups have recently questioned the necessity or desirability of this target, shifting attention to aiming for growth ...
A physiological approach to the timing of umbilical cord clamping …
WEBUmbilical cord clamping at birth has a major impact on an infant's cardiovascular system that varies in significance depending upon whether the infant has commenced breathing. As umbilical venous return is a major source of preload for the left ventricle during fetal life, recent experimental evidence has shown that clamping the umbilical cord severely limits cardiac venous return in the ...
Screening for early onset neonatal sepsis: NICE guidance-based …
WEBObjective To compare management recommendations of the National Institute for Health and Care Excellence (NICE) guidelines with the Kaiser Permanente sepsis risk calculator (SRC) for risk of early onset neonatal sepsis (EONS). Design Multicentre prospective observational projection study. Setting Eight maternity hospitals in Wales, UK. Patients All live births ≥34 weeks gestation over a 3 ...
Reference range for serum cortisol in well preterm infants
WEBAIM To establish a reference range for serum cortisol concentrations in preterm infants with a gestational age of less than 30 weeks during the first two weeks of life. METHODS Infants were prospectively classified by the following exclusion criteria: surfactant administration, arterial hypotension, acute or uncontrolled infection, ventricular haemorrhage II° or above, serum glucose < 2.2 ...