Albert Bruce Sabin: The Man Who Made the Oral Polio Vaccine
WEBThis is a photograph of Albert Bruce Sabin (1906–1993), the man who made the oral polio vaccine (Figure). Sabin’s name will always be associated with poliomyelitis, a disease that claimed millions of victims in the 20th century, particularly among children.
Albert Sabin - Wikipedia
WEBSabin developed an oral vaccine based on mutant strains of polio virus that seemed to stimulate antibody production but not to cause paralysis. Recipients of his live attenuated oral vaccine included himself, family, and colleagues.
Salk, Sabin and the Race Against Polio | Smithsonian
WEBApr 3, 2012 · Salk, Sabin and the Race Against Polio. As polio ravaged patients worldwide, two gifted American researchers developed distinct vaccines against it. Then the question was: Which one to use?
Sabin vaccine | medicine | Britannica
WEBIn polio: Treatment and vaccination …oral poliovirus vaccine (OPV), or Sabin vaccine, named for its inventor, Albert Sabin. IPV, based on killed, or inactivated, poliovirus serotypes 1, 2, and 3, was the first vaccine to break …
Sabin Saves the Day - Polio Across the Iron Curtain - NCBI Bookshelf
WEBThe safety and efficacy of live poliovirus vaccines were fertile grounds for Cold War fears and political considerations. Not only were Sabin’s and Koprowski’s vaccines new, but the whole concept of the live vaccine was novel in disease prevention.
Sabin Monovalent Oral Polio Vaccines: Review of Past Experiences …
WEBAug 15, 2001 · A new inactivated polio vaccine formulated with Sabin strains instead of wild strains could provide an economically viable means for producing large stocks of MOPV strains. Preliminary results of studies in Japan that have been evaluating Sabin-IPV have been promising .
Genetic stabilization of attenuated oral vaccines against poliovirus ...
WEBJun 14, 2023 · Vaccination with Sabin, a live attenuated oral polio vaccine (OPV), results in robust intestinal and humoral immunity and has been key to controlling poliomyelitis.
Assessment of genetic changes and neurovirulence of shed Sabin …
WEBJul 29, 2021 · Sabin-strain oral polio vaccines (OPV) can, in rare instances, cause disease in recipients and susceptible contacts or evolve to become circulating vaccine-derived strains with the potential to...
The history of polio vaccination with “Sabin’s OPV” 60 years after …
WEBMar 31, 2024 · In the spring of 1964, polio vaccination with the oral vaccine developed by Albert Sabin began in Italy. Sabin’s name became known to Italians on the occasion of the 3rd International Polio Conference, which was held in Rome in September 1954.
Sabin Strain Inactivated Polio Vaccine for the Polio Endgame
WEBFeb 3, 2020 · Sabin Strain Inactivated Polio Vaccine for the Polio Endgame. J Infect Dis. 2020 Feb 3;221 (4):504-505. doi: 10.1093/infdis/jiz077. Authors. John F Modlin 1 , Konstantin Chumakov 2. Affiliations. 1 Bill and Melinda Gates Foundation, Seattle, Washington. 2 Food and Drug Administration, Silver Spring, Maryland. PMID: 30788498.