GFAP and S100B: What You Always Wanted to Know and Never …
WEBMar 21, 2022 · Glial fibrillary acidic protein (GFAP) outperforms S100 calcium-binding protein B (S100B) and ubiquitin C-terminal hydrolase L1 (UCH-L1) as predictor for positive computed tomography of the head in trauma subjects.
GFAP and S100B: What You Always Wanted to Know and Never …
WEBMar 21, 2022 · We focus on two astrocytic proteins, S100B and GFAP, the most commonly employed biomarkers used in mTBI. We also offer recommendations that may translate into a broader acceptance of these clinical tools.
Current Trends in Stroke Biomarkers: The Prognostic Role of S100B and GFAP
WEB5 days ago · The reviewed studies highlight the potential of S100B and GFAP as significant biomarkers in the prognosis and diagnosis of patients with stroke and their ability of predicting long-term neurological deficits.
Enteric Glia: S100, GFAP, and Beyond - Grundmann - 2019 - The ...
WEBApr 5, 2019 · The in vivo S100b expression in EGCs was increased in all three investigated intestinal regions after 24 hr. GFAP expression was also upregulated in EGCs after 24 hr in all regions but earliest in the caecum.
Blood GFAP as an emerging biomarker in brain and spinal cord
WEBFeb 3, 2022 · In addition to glial fibrillary acidic protein (GFAP), calcium-binding protein B (S100B), glutamine synthetase and chitinase 3 like 1 (CHI3L1) are among the most studied biological markers for...
S100B is selectively expressed by gray matter protoplasmic …
WEBOct 6, 2021 · In the developing spinal cord, S100B is first expressed in the ventral neuroepithelial cells, and later in ALDH1L1+/GS+ astrocytes in the gray matter. Meanwhile, nearly all the S100B+ cells in the white matter are SOX10+/MYRF+ oligodendrocytes.
Targeting S100B Protein as a Surrogate Biomarker and its Role in ...
WEBS100B is a helix-loop-helix protein with the calcium-binding domain associated with various neurological disorders through activation of the MAPK pathway, increased NF-kB expression resulting in cell survival, proliferation and gene up-regulation.
Increased GFAP concentrations in the cerebrospinal fluid of …
WEBMay 21, 2021 · Glial fibrillary acidic protein (GFAP) and calcium-binding protein S100B are considered microglial markers. To date, their role has been studied in the serum and tissue material of patients...
The S100B Protein: A Multifaceted Pathogenic Factor More Than a ...
WEBMay 31, 2023 · In this respect, the use of S100B as a valuable biomarker has also been compared with the other frequently used astrocytic biomarker, Glial Fibrillary Acidic Protein (GFAP) [9,63,68,69]. In fact, the use of S100B as a screening tool, especially in mild traumatic brain injury, offered potential advantages over the use of GFAP; however ...
Fluid biomarkers of chronic traumatic brain injury - Nature
WEB3 days ago · This Review summarizes fluid biomarker findings in the chronic phase of TBI (≥6 months after injury) that demonstrate the involvement of inflammation, glial biology and neurodegeneration in the...
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